Computational Toxicology: A Useful Tool for Hazard Identification and Risk Assessment?
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Owner/Developer: American College of Toxicology (ACT)
| Country: |
United States of America |
|---|---|
| Languages: |
English |
| Url: |
https://interact.actox.org/p/cm/ld/fid=34&tid=79&sid=246 |
| Created: |
26 May 2015 |
| Description: |
In recent years, computational toxicology as a discipline has received considerable attention as it offers the attraction of being able to provide rapid assessments of toxicological hazards and/or risks at a significantly lower cost than in vivo or even in vitro assays. It also has the added attraction of reducing, refining or perhaps even eliminating the use of animals in toxicology testing. However, just how good are the computational tools available and how should they be used to draw appropriate conclusions about chemical safety? This presentation focuses on the current state of the art and highlight some of the limitations of the current approaches in computational toxicology. |
| References: |
Webinar ppt slides:
ACT_Webinar RNaven_CompTox2015.pdf |
| Format: |
Webinars |
| Presence: |
Optional / Voluntary |
| Access: |
Free |
| Content type: |
Theoretical |
| Duration: |
1h 12 min |
| Target audience: |
Students, Researchers, Regulators and policy-makers, Teachers and educators, Technicians, Managers, Scientific officers / Project managers, Professionals (e.g. veterinarians), General public |
| Target sectors: |
Academia, Industry, Governmental bodies, Contract Research Organizations (CROs), Consulting, SMEs |
| Educational level: |
Continuing Professional Development |
| 3rs relevance: |
Replacement |
| Topics covered: |
Computational methods |
| 3rs coverage: |
Full coverage (a dedicated course) |
| Details on the topic or technology covered: |
•What is computational toxicology?
•Traditional applications e.g. prediction of mutagenicity •Challenges in modelling in vitro data •Assessing predictive performance •The prediction of complex toxicological endpoints •Development of robust safety screening paradigms |
| Accreditation body and/or authority that approved the education or training: |
In collaboration with: British Toxicology Society, SOT Biological Modeling Specialty Section,
Society of Toxicologic Pathology, and the Teratology Society |
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