Rat Blood Pressure (Rat Blood Pressure)
Owner/Developer: Sheffield Bioscience Programs
| Country: |
United Kingdom |
|---|---|
| Languages: |
English |
| Url: |
http://www.sheffbp.co.uk/sbpmain.htm |
| Created: |
01 January 2008 |
| Locations: |
United Kingdom |
| City: |
Edinburgh |
| Description: |
an interactive computer simulation of experiments to study the effects of a number of pharmacological agents on rat blood pressure in vivo |
| Format: |
Computer assisted learning |
| Presence: |
Optional / Voluntary |
| Access: |
Fee-based |
| Content type: |
Theoretical |
| Target audience: |
Students |
| Target sectors: |
Academia |
| Educational level: |
Undergraduate |
| 3rs relevance: |
Replacement, Refinement |
| Topics covered: |
Carrying out procedures on animals, Computational methods |
| 3rs coverage: |
Full coverage (a dedicated course) |
| Species covered: |
Rats (Rattus norvegicus) |
| Course level on animal species: |
Advanced course |
| Details on the topic or technology covered: |
The main menu allows students to access sections covering different aspects of the laboratory class;
Introduction: Home Office Licence requirements, Preparation: anaesthesia/anaesthetization, cann-ulation of trachea, jugular vein and carotid artery, Apparatus: equipment used to maintain body temperature, record blood pressure and heart rate, Measurements: describes how to take measurements from the simulated chart recorder and how to calculate mean BP and pulse pressure, Experiments: provides typical data for 16 different experiments selected to teach the essential pharmacology: catecholamines; pressor agents ; acetylcholine; ganglion stimulants ; uptake1-blockers; alpha-blockers ; beta-blockers; adrenaline reversal ; guanethidine ; sympathetic nerve stimulation; depressor drugs ; ganglion blockade; quantitative effects of alpha-blockade; quantitative effects of beta-blockade; reserpine; pithing. Students are expected to record and tabulate data from the screen display and to then complete student assignments e.g. a series of MCQ questions, with feedback, to assess accuracy of data collection and data interpretation; a student task (typical of a traditional lab-class report) to be completed in their own time. In addition there is a section containing a selection of MCQ's with feedback covering cardiovascular pharmacology which students can use for revision. |
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