Contract between __ (animal facility) and __ (research group)

Date:

This contract describes the division of labour and responsibilities between the two parties, with the aim of clarifying all stages of the experiment and ensuring that all necessary parameters are recorded.

 

Animal facility

Researcher

Not applicable

Animal:

     

Arrival date

     

Species

     

Strain/stock and substrain

     

Supplier (full name and address) or bred on the premises

     

Number and sex

     

Age, weight, stage of life cycle on arrival

     

Pre-treatment (surgical or medical) from supplier

     

Quality (e.g. SPF, germ-free, gnotobiotic, conventional)

     

Acclimation time before the start of the experiment

     

Time and duration of fasting (with/without water and bedding)

     

Environment:

General description

     

Temperature (mean ± variation)

     

Light schedule

     

Relative humidity (mean ± variation)

     

Number of air changes in the animal room/cabinet per hour

     

Environmental enrichment (specify)

     

Housing:

Type (e.g. free-range, shelf, cabinet, isolator, single/group, barrier/conventional)

     

Cage/tank type and size

     

Number and method of distribution of animals per cage/tank

     

Frequency of cage/tank cleaning or change

     

Feed:

Manufacturer (full name and address)

     

Type (breeding, growth, maintenance diet)

     

Batch number and expiry date

     

Sterility (radiation, heat treatment, UV light)

     

Consistency (pellets, expanded, powder, mash)

     

Administration (ad libitum, rationed)

     

Litter/bedding:

Manufacturer (full name and address)

     

Type (e.g. shavings, paper, absorbable mat)

     

Batch number

     

Sterility (radiation/heat treatment)

     

Type (pellets, chips, shavings, matting)

     

Water source:

Tap water, other source

     

Quality (e.g. purification, addition of Vitamin C or hydrochloric acid, heat treatment)

     

Ad libitum, rationed

     

Experiment:

Capture and immobilisation methods, timespan

 

Identification and marking methods

     

Test substance (manufacturer, technical description, amount, method and time of administration)

     

Sedatives, anaesthetics and analgesics (manufacturer, technical description, dose, method and time of administration)

     

Clinical health assessment

Signs of pain

     

Activity level, alertness

     

Coat, skin

     

Degree of hydration

     

Respiration rate

     

The actual severity category experienced by the animal

     

Permitted treatments if an animal becomes ill or injured

     

Humane killing / release / re-homing:

     

Date and time

     

Method

     

Method of drug administration

     

Necropsy:

     

External observations

     

Procedure

     

Description of histological and other analytical techniques

     

 

New SOPs or additions to the facility's Master Plan and Contingency Plan may have to be considered.

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