Non-Clinical Vascular Infusion Technology, Volume II, The Techniques

This book, written with contributions from an international selection of authors who are leaders in commercial infusion technology, provides a current account of the techniques involved in all the major laboratory animal species for conducting successful vascular infusion studies with xenobiotics. Following in the footsteps of the highly praised Handbook of Pre-Clinical Continuous Intravenous Infusion, this new volume covers both up-to-date procedures and equipment. It is organized by species, including all those commonly used in pre-clinical studies: rat, mouse, dog, minipig, large primate, and marmoset. There are also chapters on juvenile studies and reproductive toxicity studies. Each section addresses the selection of the best model, surgical and non-surgical best practices, practical techniques, equipment selection, and commonly encountered background pathologies.

This Volume, along with Volume I: The Science, record number 8379, provides a foundation of knowledge on infusion technology and its importance for safe clinical use of substances via this route of delivery. Features: Presents step-by-step procedures and practical tips covering a wide range of common animal models, augmented by the liberal use of illustrations; Emphasizes best practices in accordance with the 3Rs: reduction, refinement, and replacement of animal usage in laboratories; Discusses pathology within each species chapter, rather than as a stand-alone chapter, and relevant equipment in each chapter; Covers catheterization techniques, including entrance and exit locations; Offers detailed information on surgical preparation for primates and minipigs, along with advice about the use of preoperative anesthesia, postsurgical analgesics, and antibiotic administration, as well as valuable input on surgical suite design. 

First Edition. Volume II. 344 pages. 146 illustrations. Available as a Paperback & Hardback. Table of Contents.

ISBN: Paperback: 781138374614, Hardback: 9781439874455

Price: Paperback: £45.59