Detection of endpoints and biomarkers of repeated dose toxicity using in vitro systems (DETECTIVE)
Owner/Developer: European Commission and Cosmetics Europe
| Country: | Germany |
|---|---|
| Languages: | English |
| Url: | http://www.detect-iv-e.eu/ |
| Contact: | http://www.detect-iv-e.eu/?page_id=21 |
| Description: |
Assessment of repeated dose toxicity is a standard requirement in human safety evaluation and relies on animal testing as no alternatives are currently accepted for regulatory purposes. An integrated research strategy for the replacement of animal tests needs to comprise the development of biomarkers of long-term toxicity in human target cells. To this aim, the DETECTIVE project will set up a screening pipeline of high content, high throughput as well as classical functional and “-omics” technologies to identify and investigate human biomarkers in cellular models for repeated dose in vitro testing. |
| Category: | Research Program/Project/Grant |
| Channel: | Face-to-face - Website - Printed |
| Audience: | Scientists - Regulators - Industry - Researchers |
| User access: | Open access |
| Updating frequency: | 2015 |
| Relevance: | Replacement |
| Purpose: | Regulatory testing - Toxicological and safety evaluation - Method development |
| Technology/Tools: | High throughput screening - High content screening - Omics - Alternative test methods (in vitro) |
Fant du det du lette etter?
Ja, jeg fant det! Nei, jeg fant det ikke!Takk for din tilbakemelding! Vær oppmerksom på at vi ikke kan kontakte deg hvis ikke du oppgir din epostadresse.
Hva lette du etter?
Gi oss gjerne en tilbakemelding slik at vi kan forbedre informasjonen på siden. På forhånd takk for hjelpen! Vennligst skriv inn din epostadresse hvis du vil ha et svar.
Kontakt oss gjerne på e-post hvis du har spørsmål.