International Cooperation on Alternative Test Methods (ICATM)
| Record number: | 53027 (legacy id: 15309) |
|---|---|
| Category: | Design - Procedures - Toxicology |
| Type: | Information centres |
| Relevance: | Reduction - Refinement - Replacement |
The ICATM was developed through a collaboration involving ICCVAM, the EURL ECVAM, the Japanese Center for the Validation of Alternative Methods (JaCVAM), and Health Canada. The goals of this framework are:
- To establish international cooperation in the critical areas of validation studies, independent peer review, and development of harmonized recommendations to ensure that alternative methods/strategies are more readily accepted worldwide
- To establish international cooperation necessary to ensure that new alternative test methods/strategies adopted for regulatory use will provide equivalent or improved protection for people, animals, and the environment, while replacing, reducing, or refining (causing less pain and distress) animal use whenever scientifically feasible
- Ensure the optimal design and conduct of validation studies that will support national and international regulatory decisions on the usefulness and limitations of alternative methods proposed for regulatory testing
- Ensure high quality independent scientific peer reviews of alternative test methods, and consistency in transparency and stakeholder involvement
- Enhance the likelihood of harmonized recommendations by validation organizations on the usefulness and limitations of alternative test methods for regulatory testing purposes
- Achieve greater efficiency and effectiveness by avoiding duplication of effort and leveraging limited resources
- Support the timely international adoption of alternative methods
An updated Memorandum of Cooperation (MOC) to add the Korean Center for the Validation of Alternative Methods (KoCVAM) to the ICATM agreement was signed in March 2011.
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