Sharing and archiving of genetically altered mice
| Record number: | f1dee (legacy id: 15358) |
|---|---|
| Category: | Housing and management |
| Type: | Guidelines |
| Relevance: | Reduction - Refinement |
To increase the opportunities for applying reduction and refinement with respect to GA mice the RSPCA convened an expert working group whose members included the Biotechnology and Biological Sciences Research Council, Cancer Research UK, the Medical Research Council and the National Centre for the Replacement, Refinement and Reduction of Animals in Research (NC3Rs).
In 2009, the working group published recommendations on the Sharing and archiving of genetically altered mice. Benefits of archiving which were discussed included:
- Reduction of animal use by minimising the number of GA animals maintained on the shelf
- Facilitation of the sharing of resources, which in itself provides more opportunity for reduction
- Minimising the need of researchers to replicate research, or reproduce resources, avoiding the need for the live transport of animals
- Provision of some insurance against loss of valuable animals caused by adverse events such as environmental disasters, disease outbreaks, genetic drift and breeding failure.
More information is available on the RSCPA website.
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