Virtual Physiology: SimVessel

SimVessel offers a virtual laboratory for the examination of smooth muscle contractions of vessels and the intestine. The experiments can be done with muscle stripes, placed in an organ bath to which physiologically relevant signal substances and widely used drugs can be added. Preparing the appropriate dilutions can be trained, as in SimHeart, in a drug laboratory.

Featured experiments:

• Comparison of phasic and tonic smooth muscle contractions.
• Illustrating the effects of muscle stretching (Bayliss effect).
• Demonstrating opposite reactions of vessels and intestine on Adrenaline and Acetylcholine.
• Examining the effects of the cholinergic receptor antagonist Atropine.
• Comparing the effects of adrenergic α- and β-receptor antagonists (Phentolamine and Propranolol).
• Illustrating the effects of the Ca2+-channel blocker Verapamil.
• Recording of dose-response curves of Adrenaline and Acetylcholine.
• Demonstrating alterations of dose-response curves by competitive and non-competitive inhibitors.

First version published December 02, 2014. Last update December 18, 2015. 

• Please watch Video; SimVessel - Preparation of isolated Smooth Muscles of the Rat. 
• Download a fully functioning DEMO Version.         

SimVessel is a part of Virtual Physiology Series that consists of 5 interactive simulation CD-ROMS:

• SimNerv 
• SimMuscle 
• SimHeart
• SimNeuron
• SimVessel  

The series covers the entire field of nerve-muscle physiology and simulates all of the classic experiments conducted by medical, dental, veterinary, biology and chemistry students. All stimulation and recording devices are freely adjustable. Mathematical algorithms guarantee for the appropriate reactions of the preparations in all situations, also considering their physiological diversity.

Programs running on all Windows platforms, from Win XP to Win 10, 32 bit as well as 64 bit
versions. SimHeart and SimVessel also include .swf files to run on MacOS.

It is part of the cLABs set produced by Professor Hans Braun (see also record numbers 5406 and 5407). 

Price: Please see Virtual-Physiology.