International Zebrafish and Medaka Course (International Zebrafish and Medaka Course)
Owner/Developer: Institute of Toxicology and Genetics / European Zebrafish Ressource Center
01 June 2017
The European Zebrafish Resource Center at the Karlsruhe Institute of Technology (KIT) is now offering for the first time a comprehensive course for working with zebrafish and medaka, targeting primarily students, doctoral candidates and scientists.
Fish models have increasingly gained importance in biomedical research during the last few decades. Particularly two teleost species, zebrafish (Danio rerio) and medaka (Oryzias latipes) have become essential model systems for analyzing gene function in vertebrates.
The theory element of this course is presented using online material accessible for participants via the ICMZ website. Theory topics – among others – include legal regulations and guidelines, ethical aspects of animal experimentation (3R, alternative concepts), biology, husbandry, breeding and feeding of zebrafish and medaka, as well as health monitoring and diseases. Other fish models in toxicology and biomedical research will be discussed. The practical elements of the course will include training in the handling, husbandry, breeding, anaesthesia, fin clipping and euthanasia of zebrafish and medaka using the facilities of the European Zebrafish Ressource Center (EZRC) and the associated KIT Institute of Toxicology and Genetics.
The course will be completed with a multiple choice examination. Those who have passed the course and examination successfully will receive a certificate confirming their specific knowledge of zebrafish and medaka as well as their skills to work with these animals meeting the legal requirements.
ETPLAS courses Germany:
Hands-on training, Lecture
Students, Researchers, Teachers and educators, Scientific officers / Project managers
University (Master), University (Doctoral education), Postdoctoral (teaching and research)
Refinement, Reduction, Replacement
Carrying out procedures on animals, Designing procedures and projects, Taking care of animals, Killing animals, Ethics
Zebrafish (Danio rerio), Other species
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The teaching content of the theoretical part includes the animal protection regulations in Germany, the ethics of animal testing as well as the 3R-concept and alternative methods. Important topics are also the biology, breeding, husbandry and nutrition of zebrafish and medaka, but also questions of the health monitoring of the animals as well as relevant illnesses. Other fish models and their significance for toxicology and biomedical research will be discussed. The practice parts are carried out in the EZRC's fish farms and in cooperation with the KIT Institute of Toxicology and Genetics. Knowledge will be imparted to the handling of the animals, to husbandry, breeding, anesthesia,
Directive 2010/63/EU or equivalent
The course concludes with a performance assessment in the form of a multiple choice exam. Participants who have successfully completed both the course and the exam will receive a certificate attesting to the necessary knowledge of zebrafish and medaka, as well as their ability to handle these animals, in order to comply with the legal requirements Working with fish is enough.
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