Performance of the zebrafish embryo test for acute toxicity
This record is part of
a dataset collected by the EU Commission in June-September 2018
. Some of these links will therefore die out with time.
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overview of courses maintained by ETPLAS
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Owner/Developer: VITO (VITO)
| Country: |
Belgium |
|---|---|
| Languages: |
Dutch |
| Created: |
01 December 2015 |
| Locations: |
Belgium |
| City: |
Mol |
| Description: | Hands on training including steps maintenance zebrafish, set up breeding pairs, collection and evaluation of fertilized zebrafish eggs, experimental set up and exposure to test solutions, positive and negative control, evaluation procedure & data analysis (see OECD guideline 236, or ISO 15088 and Flemish WAC/V/B/002 procedure) |
| References: | Documents on line available : OECD guideline 236 & Flemish Guideline WAC/V/B/002 through EMIS website Course documentation & materials available at VITO |
| Format: |
Hands-on training |
| Presence: |
Mandatory |
| Access: |
Fee-based |
| Content type: |
Theoretical, Practical |
| Duration: |
2 days |
| Group size: |
3.0 |
| Frequency: |
Not defined |
| Prerequisites: |
Lab experience |
| Target audience: |
Students, Researchers, Technicians |
| Target sectors: |
Academia, Industry, Contract Research Organizations (CROs) |
| Educational level: |
High school, Technical College, Undergraduate, University (Bachelor), University (Master), University (Doctoral education), Postdoctoral (teaching and research), Continuing Professional Development |
| 3rs relevance: |
Replacement |
| Topics covered: |
Carrying out procedures on animals, Taking care of animals, In vitro methods |
| 3rs coverage: |
Full coverage (a dedicated course) |
| Species covered: |
Zebrafish (Danio rerio) |
| Details on the topic or technology covered: |
Replacement of acute toxicity test with juvenile fish, by zebrafish embryo (< 5 days) considered a non-animal model during 1st days of development according to EU legislation. This is an alternative model, but whole organism approach |
| Legislative framework: |
Directive 2010/63/EU or equivalent, REACH Regulation (EC) No 1907/2006 or equivalent, Test guidelines (OECD, ISO, etc.) |
| Learning outcome: |
practical training & theoretical background to perform the zebrafish embryo test |
| Qualification received: |
Certificate of training is given (VITO document) |
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