Enhancing search efficiency by means of a search filter for finding all studies on animal experimentation in PubMed

By Hooijmans, Carlijn R., Tillema, Alice, Leenaars, Marlies, Ritskes-Hoitinga, Merel

Collecting and analysing all available literature before starting an animal experiment is important and it is indispensable when writing a systematic review (SR) of animal research. Writing such review prevents unnecessary duplication of animal studies and thus unnecessary animal use (Reduction). One of the factors currently impeding the production of ‘high-quality’ SRs in laboratory animal science is the fact that searching for all available literature concerning animal experimentation is rather difficult. In order to diminish these difficulties, we developed a search filter for PubMed to detect all publications concerning animal studies. This filter was compared with the method most frequently used, the PubMed Limit: Animals, and validated further by performing two PubMed topic searches. Our filter performs much better than the PubMed limit: it retrieves, on average, 7% more records. Other important advantages of our filter are that it also finds the most recent records and that it is easy to use. All in all, by using our search filter in PubMed, all available literature concerning animal studies on a specific topic can easily be found and assessed, which will help in increasing the scientific quality and thereby the ethical validity of animal experiments.



Issued: July 2010

Journal Title: Laboratory animals

ISSN: 0023-6772

Volume issue: 44 v. 3 no.

Pages: 170 - 175

AGRICOLA identifier: IND44427183

DOI identifier: 10.1258/la.2010.009117
This page was updated on 04 March 2019

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