Strathclyde Pharmacology Simulations: The Virtual NMJ (Neuromuscular Junction)

The Virtual NMJ (Neuromuscular Junction) belongs to The Strathclyde Pharmacology Simulations package that simulates pharmacological experiments on isolated tissues or whole animals. A range of drugs in varying concentrations can be applied and the effects observed. The Virtual NMJ is a simulation of an experiment recording the electrical potentials associated with neuromuscular transmission at the skeletal neuromuscular junction. The simulation allows the user to observe the muscle action potential (AP) and endplate potentials (EPPs) evoked by either nerve stimulation or by direct current stimulation of the muscle fibre. The effects of a variety of drugs and of changes to ionic composition of the extracellular solution on the AP and EPPs can be studied.

Installation information is available on this page.

Please see The Virtual Cat, The Virtual RatCVS, The Virtual Nerve, The Virtual Twitch, EPSim (Rat Brain Slice Epilepsy Simulation) and OBSIM (Organ Bath Simulation) for the other simulations in this package.

Please read the Conditions under which the software may be used.

Computer program: Windows 95 or later

Version: Version 2.1.8, 2005

Price: Academic users, others working for non-commercial, non-profit making organisations: Free of charge. Commercial organisations: Purchase a license to use the software from the University of Strathclyde (contact the author for details).

See also the physiology and pharmacology programs produced by David Dewhurst for similar resources.