1-Literature searches

Literature searches help to:

• identify possible non-animal alternatives to all or part of the proposed study
• prevent unnecessary repetition of animal studies
• identify efforts to reduce animal numbers
• identify refinements to procedures in the planned study

Literature searches should address:

1. The likelihood of reproducibility of the studies in another location.
2. The likelihood, if relevant, of translatability to other species including Man.

Topics which may affect the validity, reproducibility and translatability of animal experiments are discussed under a section of concerns about experimental design.

This page was updated on 29 June 2021