CalcuSyn, Version 2.0
By Biosoft
| Record number: | 0df40 (legacy id: 639) |
|---|---|
| Category: | Biochemistry - Pharmacology |
| Type: | Computer Program |
This product is no longer available from BIOSOFT.
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CalcuSyn Version 2.0 was the analyzer of combined drug effects, able automatically to quantify phenomena such as synergism and inhibition. CalcuSyn performed multiple drug dose-effect calculations using the Median Effect methods described by T-C Chou and P. Talalay (Trends Pharmacol, Sci. 4, 450-454). CalcuSyn could easily be integrated with other software. Data could be entered via the keyboard or file import either into the grid or directly into the analysis engine. Data could be processed both for individual drugs, and for constant-ratio or non-constant-ratio combinations of drugs. CalcuSyn automatically graphed the data and produced reports giving summary statistics on all drugs plus detailed analysis of drug interactions including the Combination Index and EDx (for any value of x). Estimates of accuracy of EDx and CI could be calculated with Monte Carlo simulations or by a highly accurate algebraic estimation algorithm. The plots drawn by CalcuSyn included dose-effect, median-effect, isobolograms and CI-effect.
Version: 2.0
See also these computer simulations in pharmacology and physiology.
Free of charge Downloadable Demo: Free of charge
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