OECD Guidance document on the recognition, assessment and use of clinical signs as humane endpoints for experimental animals used in safety evaluation

AAALAC International cites these guidelines as one of its reference resources.

Issued in November 2000, 39 pages.
Covers definitions, guiding principles, initial considerations, recognition and assessment of pain, distress and suffering as an approach to detecting clinical signs and abnormal conditions, making an informed decision to humanely kill animals, methods for humane killing, guidance on the humane conduct of specific types of toxicity testing, references and annexes.
AAALAC International cites these guidelines as one of its reference resources.

This page was updated on 04 January 2022

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