Advancing Adverse Outcome Pathways for Integrated Toxicology and Regulatory Applications
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Owner/Developer: International group
| Country: |
Italy |
|---|---|
| Languages: |
English |
| Url: |
http://www.saaop.org/workshops/somma.html |
| Created: |
02 March 2014 |
| Founding source: |
American Chemistry Council, BioDetection Systems, European Centre for Ecotoxicology and Toxicology of Chemicals, Environment Canada, European Commission Directorate General Joint Research Center, Human Toxicology Project Consortium, International Life Sciences Institute - Health and Environmental Science Institute, Norwegian Institute for Water Research, Society for Environmental Toxicology and Ch |
| Locations: |
Italy |
| City: |
Somma Lombardo |
| Description: | This workshop focused on the use of the Adverse Outcome Pathway (AOP) concept as a framework to characterize, organize, and define predictive relationships between measurable key events that reflect the progression from a chemical-induced perturbation to an adverse outcome considered relevant to regulatory decision-making. |
| References: | http://www.saaop.org/workshops/index.html |
| Format: |
Workshops |
| Presence: |
Optional / Voluntary |
| Content type: |
Theoretical, Practical |
| Duration: |
5 days |
| Frequency: |
One-time event |
| Target audience: |
Regulators and policy-makers, Researchers |
| Target sectors: |
Governmental bodies, Academia, Industry |
| Educational level: |
Continuing Professional Development |
| 3rs relevance: |
Replacement |
| Topics covered: |
Computational methods |
| 3rs coverage: |
Partial coverage (e.g. a module) |
| Details on the topic or technology covered: |
Research priorities for development of AOPs Strategic approaches to AOP development Weight of evidence evaluation to define uncertainties associated with predictive relationships represented in an AOP “Acceptance” of AOPs for regulatory applications Applying AOPs to support Informed Approaches to Testing and Assessment |
| Legislative framework: |
Test guidelines (OECD, ISO, etc.) |
| Learning outcome: |
The objective of the present workshop was to build upon these previous efforts and provide consideration and expert opinion on the critical next steps required to advance the use and acceptance of the AOP framework to support integrated toxicology and regulatory decision-making |
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