Strathclyde Pharmacology Simulations: The Virtual Twitch

By John Dempster

The Virtual Twitch belongs to The Strathclyde Pharmacology Simulations package that simulates pharmacological experiments on isolated tissues or whole animals.   Type of record: Computer Program and Web Pages. Category: Pharmacology

Virtual Twitch pharm

The Virtual Twitch belongs to The Strathclyde Pharmacology Simulations package that simulates pharmacological experiments on isolated tissues or whole animals. A range of drugs in varying concentrations can be applied and the effects observed. The Virtual Twitch is a simulation of the rat phrenic nerve-hemidiaphragm preparation used to study the actions of neuromuscular blocking and reversal agents, and other drugs which affect neuromuscular transmission. The hemidiaphraghm is a large, focally innervated, respiratory skeletal muscle, composed of fast-type muscle fibres. Electrical stimulation of the phrenic nerve evokes fast, shorting-lasting muscle twitches. 

Installation information is available (please scroll down to the bottom of the page).

Please see The Virtual Cat, The Virtual RatCVS, The Virtual Nerve, OBSIM (Organ Bath Simulation), EPSim (Rat Brain Slice Epilepsy Simulation) and The Virtual NMJ (Neuromuscular Junction) for the other simulations in this package. 

Please read the Conditions under which the software may be used.

Version: Version 2.2.1, 2014

Computer program: Windows 95 or later

Price: Academic users, others working for non-commercial, non-profit making organisations: Free of charge. Commercial organisations: Purchase a license to use the software from the University of Strathclyde (contact the author for details).

See also the physiology and pharmacology programs produced by David Dewhurst for similar resources.

This page was updated on 26 April 2022

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