International Mouse Phenotyping Consortium (IMPC)

The IMPC project is in the process of generating a knockout mouse strain for every protein encoding gene by using the embryonic stem cell resource of the International Knockout Mouse Consortium (IKMC).

The International Mouse Phenotyping Consortium is in the process of generating a knockout mouse strain for every protein encoding gene by using the embryonic stem cell resource by the International Knockout Mouse Consortium (IKMC). The production of mouse strains from these ES cells are tracked within the "international Micro-injection tracking system" (iMits) and are made available to the research community via public repositories.

Systematic broad-based phenotyping is performed by each IMPC centre using standardised phenotype protocols found within the International Mouse Phenotyping Resource of Standardised Screens (IMPReSS) resource. Gene-to-phenotype associations are made by statistical analysis with all data freely available by this web portal and by several data download features. The IMPC website also includes a search engine for disease models.

See also Norecopa's collection of links to alternatives databases

This page was updated on 14 March 2025
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