Advanced course in Laboratory Animal Science – Focus on the Porcine Model
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Owner/Developer: Aarhus University (AAU)
| Country: |
Denmark |
|---|---|
| Languages: |
Danish, English |
| Url: |
https://au.phd-courses.dk/CourseCatalog/ShowCourse/669?returnUrl=%2F |
| Created: |
01 January 2017 |
| Locations: |
Denmark |
| City: |
Aarhus |
| Description: | Give the participants insight in how to conduct valuable and high-quality research projects with the pig as research model. There will be lectures on legislation and how to apply for permission to perform animal experiments. Apart from gaining the knowledge of do’s and don’ts within the field, the course participants will have time to make a draft for a licence application themselves and be introduced to basic concepts such as severity assessment and humane endpoints. A paramount focus will be on anesthesia and analgesia of the pig, in order for the participants to be able to draft and perform a suitable anesthesia and analgesia protocol, and make thorough decisions on every aspect from pre-anesthetic agent to the postoperative pain relieve management and surveillance. This will be followed by a day of practical exercises. Here, the participants will have hands-on experience anesthetizing pigs and performing general surgical procedures. Participants will be taught in the concept of ARRIVE-guidelines, the 3Rs, systematic review procedures as well as pitfalls when evaluating research results in swine and possible confounders to research results to consider. The aim here is to focus on the translational value. There will also be a brief touch upon precautions to avoid zoonoses and for finalization of the course there will be a one-hour test. |
| Format: |
Hands-on training, Lecture |
| Presence: |
Mandatory |
| Access: |
Free, Fee-based |
| Content type: |
Theoretical, Practical |
| Duration: |
5 days |
| Group size: |
16.0 |
| Frequency: |
Recurrent event |
| Prerequisites: |
University degree in medicine, dentistry, nursing, or Master’s degree in other fields and/or postgraduate research fellows (PhD students and research-year medical students). Participants have preferably already attended the basic course in Laboratory Animal Science. |
| Target audience: |
Students, Researchers |
| Target sectors: |
Academia |
| Educational level: |
University (Doctoral education), Postdoctoral (teaching and research), Continuing Professional Development |
| 3rs relevance: |
Refinement |
| Topics covered: |
Carrying out procedures on animals, Designing procedures and projects, Taking care of animals, Ethics, Legislative aspects |
| 3rs coverage: |
Substantial coverage (e.g. multiple modules) |
| Species covered: |
Pigs (Sus scrofa domesticus) |
| Course level on animal species: |
Advanced course |
| Details on the topic or technology covered: |
- Hands-on training in the use of swine as biomedical research models - How to apply for permission to perform animal experiments including severity assessment and beforehand evaluation of humane endpoints - Anesthesia and analgesia of the pig - Venipuncture, injection, intubation, anesthesia and analgesia, surgical procedures such as IV access, suturing, thoracic and abdominal surgical procedures |
| Legislative framework: |
Directive 2010/63/EU or equivalent |
| Learning outcome: |
Knowledge: - Legislation and how to write an application to perform animal experiments - Advanced anesthesia, analgesia and euthanasia of Swine. Both in theory and hands on knowledge - Basic concepts of surgical instrumentation of pigs - The principles of planning and designing procedures and projects, as well as evaluating studies using live animals, specifically swine - How to evaluate the translational value of animal studies - Theoretical and practical use of replacement, reduction and refinement in the design and performance of animal experiments Skills: - Evaluate what models and principles of procedures can be used on their future experiments - The legislation within the field - Consider severity as well as humane endpoints - Make a draft for a protocol for advanced anesthesia, analgesia and euthanasia of Swine - The basic concepts of surgical instrumentation of pigs - The principles of planning and designing procedures and projects, as well as evaluating studies using live animals, specifically swine - How to evaluate the translational value of animal studies - The theoretical and practical use of replacement, reduction and refinement in the design and performance of animal experiments - Reflect over the ethical basis for the use of animals for research Competencies: - Perform basic anesthesia and analgesia procedures in pigs - Perform basic surgical instrumentation of pigs in research - Apply for a licence to perform research experiments in swine and have accomplished sufficient knowledge to evaluate severity and humane endpoints. - Perform translational research with consideration to both quality and ethics |
| Accreditation body and/or authority that approved the education or training: |
by the university |
| Qualification received: |
ECTS: 4.1 |
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