Application of non-animal approaches for decision-making in chemical safety assessment
This record is part of
a dataset collected by the EU Commission in June-September 2018
. Some of these links will therefore die out with time.
Please see the
overview of courses maintained by ETPLAS
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Owner/Developer: National Center for the Replacement, Refinement & Reduction of Animals in Research (NC3Rs)
| Country: |
United Kingdom |
|---|---|
| Languages: |
English |
| Created: |
10 December 2018 |
| Founding source: |
https://www.nc3rs.org.uk/about-us/funders |
| Locations: |
United Kingdom |
| City: |
London |
| Description: |
Unilever and the NC3Rs hosted a two-day workshop in central London on 10-11 December 2018. |
| Format: |
Workshops |
| Presence: |
Optional / Voluntary |
| Access: |
Free |
| Content type: |
Theoretical |
| Duration: |
2 days |
| Target audience: |
Professionals (e.g. veterinarians), Scientific officers / Project managers, Managers, Technicians, Teachers and educators, Regulators and policy-makers, Researchers |
| Target sectors: |
SMEs, Consulting, Contract Research Organizations (CROs), Governmental bodies, Industry, Academia |
| Educational level: |
Continuing Professional Development |
| 3rs relevance: |
Replacement |
| Topics covered: |
In vitro methods, Computational methods, Legislative aspects |
| 3rs coverage: |
Full coverage (a dedicated course) |
| Details on the topic or technology covered: |
Non-animal approaches (i.e. in vitro and in silico) can provide useful information to inform decision-making for chemical safety assessment in product development programmes. However, there can be a lack of confidence in these methods, particularly within a regulatory setting. Methods that focus on mechanistic approaches and incorporation of exposure science can make non-animal approaches more useful for decision-making purposes, and can therefore support a reduction in the current reliance on data from animal tests. The meeting brought together academic and industry researchers across multiple disciplines to share their knowledge and experiences in applying non-animal (i.e. in vitro and in silico) methods for decision-making for efficacy and safety assessment. The workshop was attended by expert scientists from academia, government and regulatory agencies and the (agro)chemicals, consumer products, and pharmaceutical industries. The key objectives of the workshop were to: Showcase how non-animal approaches (i.e. in vitro and in silico) are currently being used to enable and improve decision-making for chemical safety assessment, including the use of AOPs/mechanistic approaches and incorporation of exposure science. Increase awareness and acceptance of non-animal approaches to accelerate their uptake to support decision-making, particularly in a regulatory setting. Identify scientific gaps that if addressed could have a significant impact on the application and uptake of non-animal approaches. Encourage collaboration between sectors, to share knowledge and ‘lessons learned’ to maximise the impact of non-animal approaches and to improve safety and efficacy decision-making. |
| Legislative framework: |
Directive 2010/63/EU or equivalent |
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