Humane endpoints in laboratory animal experimentation
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a dataset collected by the EU Commission in June-September 2018
. Some of these links will therefore die out with time.
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Owner/Developer: 3Rs Centre Utrecht Life Sciences (3Rs Centre ULS)
01 January 2016
Triodos foundation, utrecht life sciences, utrecht university, fstal, universidad de alcala, zonmw, kfheinfonds, laboratory animals limited
This website is the tool to make animal experimentation more humane while improving the quality of science.
gives you guidance on how to apply humane endpoints
includes a wealth of information on humane endpoints and related aspects, such as:
normal behaviour of rats and mice
clinical signs and pathology
pain & distress
has an extensive database of videos and photographs of clinical indications as well as relevant laws & regulations and of literature
trains you how to monitor welfare, identify endpoints and define responsibilities
and has an interactive educational component for training purposes
In general, the website is designed to help you to refine your experiments, improve your knowledge of the welfare of the animals and to improve the scientific quality of your research.
Interactive online resources
Optional / Voluntary
Students, Researchers, Regulators and policy-makers, Teachers and educators, Technicians, Managers, Scientific officers / Project managers, Professionals (e.g. veterinarians), General public
Academia, Industry, Governmental bodies, Contract Research Organizations (CROs), Consulting, SMEs
University (Bachelor), University (Master), University (Doctoral education), Postdoctoral (teaching and research), Continuing Professional Development
Ethics, Legislative aspects, Carrying out procedures on animals, Taking care of animals
Full coverage (a dedicated course)
Mice (Mus musculus), Rats (Rattus norvegicus), Zebrafish (Danio rerio)
|Course level on animal species:||
|Details on the topic or technology covered:||
1. Normal behaviour and physiology
2. Observation and monitoring
3. Laws and regulations
5. Pain and distress
6. General clinical signs
7. Deviant spontaneous behaviours
8. Specific clinical signs
10. Application of humane endpoints
11. E-learning and training modules
Directive 2010/63/EU or equivalent, Institute for Laboratory Animal Research (ILAR), Test guidelines (OECD, ISO, etc.)
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