Prolonged Pain Research in Mice: Trends in Reference to the 3Rs
Owner/Developer: Journal of Applied Animal Welfare Science
This literature review documents trends in the use of mice in prolonged pain research, defined herein as research that subjects mice to a source of pain for at least 14 days. The total amount of prolonged pain research on mice has increased dramatically in the past decade for the 3 pain categories examined: neuropathic, inflammatory, and chronic pain. [...] Finally, although most authors referred to approval of
experiments by an institutional nonhuman animal use committee, there were no references to the “3Rs” in a random selection of 55 papers examined.
|Audience:||Scientists - Researchers|
|User access:||Restricted access|
|Relevance:||Replacement - Reduction - Refinement|
|Purpose:||Documentation and information|
|Technology/Tools:||Animal testing (in vivo)|
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