Prolonged Pain Research in Mice: Trends in Reference to the 3Rs
Owner/Developer: Journal of Applied Animal Welfare Science
| Country: | United Kingdom |
|---|---|
| Languages: | English |
| Url: | http://www.tandfonline.com/doi/abs/10.1080/10888705.2013.741004?tab=permissions&scroll=top |
| Description: |
This literature review documents trends in the use of mice in prolonged pain research, defined herein as research that subjects mice to a source of pain for at least 14 days. The total amount of prolonged pain research on mice has increased dramatically in the past decade for the 3 pain categories examined: neuropathic, inflammatory, and chronic pain. [...] Finally, although most authors referred to approval of experiments by an institutional nonhuman animal use committee, there were no references to the “3Rs” in a random selection of 55 papers examined. |
| Category: | Information System |
| Channel: | Website |
| Audience: | Scientists - Researchers |
| User access: | Restricted access |
| Updating frequency: | 2013 |
| Relevance: | Replacement - Reduction - Refinement |
| Purpose: | Documentation and information |
| Technology/Tools: | Animal testing (in vivo) |
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