Sample collection
|
Source |
Non-harmful / below threshold / severity degree 0 | Mild / severity degree 1 | Moderate / severity degree 2 | Severe / severity degree 3 |
| Federal Food Safety and Veterinary Office FSVO (2018) |
Euthanasia of fetuses or premature animals in the last third of gestation or development for the collection of body fluids, tissues, organs or body parts by methods in conformity with the Animal Protection Act (including reptiles and birds). Where tissue is collected from fetuses whose mother has been put under deep anaesthesia and is euthanized within 5 to 10 minutes after the onset of anaesthesia, this is classed as euthanasia without pretreatment. |
Collection of fluids or tissue resulting in mild impairment of the young animals’ further development. Examples: Venous blood collection in premature calves. |
Collection of fluids or tissue resulting in moderate impairment of the young animals’ further development. | Collection of fluids or tissue resulting in severe impairment of the animals’ further development or death/abortion. |
Feeding
|
Source |
Non-harmful / below threshold / severity degree 0 | Mild / severity degree 1 | Moderate / severity degree 2 | Severe / severity degree 3 |
| Federal Food Safety and Veterinary Office FSVO (2018) |
Restriction of food/energy intake to investigate developmental influences on adult diseases with mild impairments of the foetus or premature animal. | Restriction of food/energy intake to investigate developmental influences on adult diseases with moderate impairments of the foetus or premature animal. | Restriction of food/energy intake to investigate developmental influences on adult diseases with severe impairments of the foetus or premature animal. |
Surgical interventions
|
Source |
Non-harmful / below threshold / severity degree 0 | Mild / severity degree 1 | Moderate / severity degree 2 | Severe / severity degree 3 |
| Federal Food Safety and Veterinary Office FSVO (2018) |
Intrauterine interventions on the foetus. Example: Intrauterine use of instruments (ECG, EEG recordings) in a ruminant foetus in utero. |
Reproductive toxicology
|
Source |
Non-harmful / below threshold / severity degree 0 | Mild / severity degree 1 | Moderate / severity degree 2 | Severe / severity degree 3 |
| Federal Food Safety and Veterinary Office FSVO (2018) |
Testing of substances for teratological effects resulting in moderate consequences. Examples: Substances causing malformations with moderate constraint but not leading to death. |
Testing of substances for teratological effects resulting in severe consequences. Examples: Abortion, severe malfomations with or without fatal consequences. |
||
| Federal Food Safety and Veterinary Office FSVO (2018) | Use of embryos, foetuses or larvae for experimental purposes if they survive the date of birth, hatching or metamorphosis and only mild impairments of the animals are expected. |
Use of embryos, foetuses or larvae for experimental purposes if they survive the date of birth, hatching or metamorphosis and only moderate impairments of the animals are expected. Collection of germ cells or non-viable developmental stages for experimental purposes from living parent animals (all species including Xenopus). Examples: Mouse strains produced using oncogenes, if the termination criteria are selected accordingly. Chemical and radiation-induced mutagenesis for the production of animal lines with defects. |
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