FDA Forced to Release Disturbing Video of Nicotine Experiments on Monkeys

Following an exclusive expose by Rare in March 2017, the FDA's Arkansas-based National Center for Toxicological Research canceled the...<br/><br/>'s Arkansas-based National Center for Toxicological Research canceled the animal experiments and released dozens of squirrel monkeys into a

PLK1 has tumor-suppressive potential in APC-truncated colon cancer cells

Abstract The spindle assembly checkpoint (SAC) acts as a molecular safeguard in ensuring faithful chromosome transmission during mitosis,...<br/><br/>the ZFE (Goethe University, Frankfurt). Details of the animal experiments that may influence results were included in the manuscript based

Targeted metabolomic profiling in rat tissues reveals sex differences

Abstract Sex differences affect several diseases and are organ-and parameter-specific. In humans and animals, sex differences also...<br/><br/>law (DL 116, 1992) and the National Institutes of Health principles of laboratory animal care (NIH 80–33, revised 1996), and approved by the

Humanized Mouse Model Market Analysis and Forecast Study for 2017 – 2027

The use of genetically engineered mice in experimental medical research have led to significant advances to understand the disease and...<br/><br/>in life sciences sector, research in regenerative medicines, increase in animal research, rising focus on personalized medicines, growth in

Notch2 controls hepatocyte-derived cholangiocarcinoma formation in mice

Abstract Liver cancer comprises a group of malignant tumors, among which hepatocellular carcinoma (HCC) and intrahepatic...<br/><br/>, fed, and monitored according to protocols approved by the Committee for Animal Research at the University of California San Francisco (San

Denne tabben kan gi alvorlig helseskade – nå fjerner Swix videoen

Swix endrer instruksjonsvideo som viser hvordan man smører ski med glidprodukter. Gjør man som i videoen, kan man bli alvorlig syk.<br/><br/>kan gi økt kolesterol, hormonforstyrrelser og vaksineresistens, og dyreforsøk gjør at det mistenkes å blant annet være kreftfremkallende.

New Vaccine Formulations Containing a Modified Version of the Amastigote 2 Antigen and the Non-Virulent Trypanosoma cruzi CL-14 Strain Are Highly Antigenic and Protective against Leishmania infantum Challenge

Visceral leishmaniasis (VL) is a major public health issue reported as the second illness in mortality among all tropical diseases....<br/><br/>according to animal welfare guidelines of the Ethics Committee of Animal Experimentation from Federal University of Minas Gerais under the

Eastern quoll returns to mainland Australia

The eastern quoll, a small furry marsupial, had been considered extinct on mainland Australia for almost 50 years. In a conservation...<br/><br/>" bats are not a popular area of research in Australia. Australia's animal research: the good, the bad and the ugly animals Red fox Under

Wild Earth Introduces Cultured Clean Protein for $30B Pet Food Market

BERKELEY, Calif., March 15, 2018 --Â Wild Earth, Inc., a biotech startup, announced today it is using cultured proteins to develop clean,...<br/><br/>conducted by volunteers and animals living in homes, as opposed to caged laboratory animals as in conventional pet foods. These humane, non-

Toosendanin inhibits adipogenesis by activating Wnt/β-catenin signaling

Abstract Toosendanin (TSN), a triterpenoid extracted from Melia toosendan, has been reported to possess anti-oxidant, anti-inflammatory,...<br/><br/>authors confirmed that all animals received human care and all animal experiments were performed in accordance with the relevant guidelines

On-target action of anti-tropomyosin drugs regulates glucose metabolism

Abstract The development of novel small molecule inhibitors of the cancer-associated tropomyosin 3.1 (Tpm3.1) provides the ability to...<br/><br/>-7 (DavosPharma) adjusted to pH 6.8. Mice Animal experiments were performed in accordance with UNSW Australia Animal Care and Ethics

LMTK3 confers chemo-resistance in breast cancer

Abstract Lemur tyrosine kinase 3 (LMTK3) is an oncogenic kinase that is involved in different types of cancer (breast, lung, gastric,...<br/><br/>Experimental protocols had been approved by the Ethics Committee for Animal Experimentation. The experimental protocol was registered by the

CEDAR farm recognized for environmental research innovation

A farm conducting world leading dairy research has celebrated 25 years since it first opened, by being named as an innovation hub for...<br/><br/>state of the art scientific facility for applied and strategic large animal research. Their extensive research capability, looking at areas

OTC antihistamines could be linked to infertility in men

Researchers from the Institute of Biology and Experimental Medicine, in Argentina, have cautioned against overuse of antihistamines.<br/><br/>be linked to impaired fertility in men, a study using animal research suggests. Published in the journal Reproduction, researchers found

Laboratory balancing act

How a stem-cell biologist approaches his work with animals.<br/><br/>my mind, I would steer my career towards projects that do not require animal research, such as those involving cell culture. How do your

Stephen Hawking's political views

World-renowned for his scientific work, Prof Stephen Hawking was also a keen student of politics, with sometimes controversial views.<br/><br/>research is ridiculous," he said. "Why is it worse to use animal experiments to save lives than to eat them, which the majority of the

Bidirectional coordination of actions and habits by TrkB in mice

Abstract Specific corticostriatal structures and circuits are important for flexibly shifting between goal-oriented versus habitual...<br/><br/>in concordance with The Guide for the Care and Use of Laboratory Animals. Intracranial surgery Mice were anaesthetized with ketamine/

Plasmodium falciparum Liver Stage Infection and Transition to Stable Blood Stage Infection in Liver-Humanized and Blood-Humanized FRGN KO Mice Enables Testing of Blood Stage Inhibitory Antibodies (Reticulocyte-Binding Protein Homolog 5) In Vivo

The invention of liver-humanized mouse models has made it possible to directly study the preerythrocytic stages of Plasmodium falciparum....<br/><br/>out in accordance with the recommendations of the NIH Office of Laboratory Animal Welfare standards (OLAW welfare assurance # A3640-01). The

Brukar omstridd halsband for å unngå skrantesjuke

Villrein i Nordfjella hadde store isklumpar på satellitthalsbanda. No får fem friske reinsdyr liknande halsband for å unngå skrantesjuke....<br/><br/>dyr som del av handteringa av ei hending. Det er ikkje eit dyreforsøk, seier Grimstad, som avviser påstandane frå Krag. Samstundes vedgår

Animal numbers in Czech Republic rise 0.6% in 2017

Editors Note: In previous years‘ reports in the Czech Republic, we reported the number of procedures on animals (as required by the EU). We...<br/><br/>. Mice, rats, birds and fish together accounted for 95% of animal research, similar to other European countries. According to the Annual

GlaxoSmithKline PLC Annual Financial Report

13/03/2018 2:10pm UK Regulatory (RNS & others) TIDMGSK RNS Number : 5943H GlaxoSmithKline PLC 13 March 2018 GlaxoSmithKline plc (the...<br/><br/>and they are generally mandated by regulators and ethically imperative. Animal research can provide critical information about the causes of

Global Next-generation Sequencing Market

Next Generation Sequencing (NGS) Market The Global Next Generation Sequencing Market is expected to reach USD XX million by 2022 from USD...<br/><br/>medicine, genetic screening, diagnostics/infectious diseases, agricultural and animal research, and others), by technology (whole genome

The dynamics of TGF-β in dental pulp, odontoblasts and dentin

Abstract Transforming growth factor-beta (TGF-β) is critical for cell proliferation and differentiation in dental pulp. Here, we show the...<br/><br/>dental pulp, odontoblasts and dentin. Full size image Methods All animal experiments, except for “Changes in dentin composition over time

Role of monkeys in the sylvatic cycle of chikungunya virus in Senegal

Abstract Arboviruses spillover into humans either as a one-step jump from a reservoir host species into humans or as a two-step jump from...<br/><br/>sylvatic cycle in the Americas. Methods Ethics statement All animal research was approved by the Institutional Animal Care and Use

Virtual Lab Rats Could Replace Living Animals in Early Drug Testing

Rats, mice, rabbits, and other animals have long been an essential part of testing drugs for safety and efficacy before they make their way...<br/><br/>89 percent of the time. And it even seemed to outperform similar animal research: Drug trials on heart cells taken from rabbits only matched

CRISPR-Based System Identifies New Drug Targets in Aggressive Leukemia

Scientists at Cold Spring Harbor Laboratory (CSHL) have discovered a way to rein in an overactive protein that drives some aggressive...<br/><br/>it will be possible to develop drugs that target these enzymes. Animal experiments are already under way in his lab to begin to investigate

Emergence of Serotonergic Neurons After Spinal Cord Injury in Turtles

Plasticity of neural circuits takes many forms and plays a fundamental role in regulating behavior to changing demands while maintaining...<br/><br/>was carried out in accordance with the recommendations of the local National Committee for Animal Research (CNEA). The protocol (#005-09-

Zebrafish Lacking Circadian Gene per2 Exhibit Visual Function Deficiency

The retina has an intrinsic circadian clock, but the importance of this clock for vision is unknown. Zebrafish offer many advantages for...<br/><br/>. The protocol was approved by the Committee on the Ethics of Animal Experiments of the USTC (Permit Number: USTCACUC1103013). Optokinetic

Metazoan Parasite Vaccines: Present Status and Future Prospects

Eukaryotic parasites and pathogens continue to cause some of the most detrimental and difficult to treat diseases (or disease states) in...<br/><br/>, is the presence of parasites that do not have effective laboratory animal models and/ or require large animal hosts for propagation and

Computer simulations move step closer to reducing animal use in drug testing

An Oxford University computer science team has developed original software which predicts clinical risk of drug-induced side effects for...<br/><br/>drug-induced side effects for the heart with higher accuracy than animal experiments. Image credit: Shutterstock The march towards replacing

    Did you find what you were looking for?

    Yes, I found it! No, I did not!

    Thanks for your feedback! Please note that we cannot respond unless you supply your email address.

    What are you looking for?

    Please give us your feedback so we can improve the information on the page. Thank you in advance for your help. Please add your email address if you would like a reply.

    Please contact us by email if you have any questions.

    Thanks for your feedback! Please note that we cannot respond unless you supply your email address.


    Abonnér på nyhetsbrevene fra Norecopa