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Ecology of Food: to Eat or Not to Eat

We all ask ourselves this question when choosing groceries. We really want to buy something truly good for our health! Those who are not on...<br/><br/>able to establish that the substances it contains can increase the life span of laboratory animals two times over. I would love to work on

Feature-packed Cosmetorium

The third edition of Cosmetorium will feature the participation of 126 companies in the sector offering visitors innovative developments in...<br/><br/>in cosmetics, and current legislation about cosmetovigilance and animal experimentation.  As keynote speakers, Cosmetorium 2018 will have

Comparing passive measures of fatigue-like behavior in mice

Fatigue is a very common and costly symptom associated with various diseases and disorders. Nonetheless, understanding the pathobiology and...<br/><br/>study were in compliance with The Guide for the Care and Use of Laboratory Animals. Animals Male C57Bl/6 mice were ordered from Charles

Plantevernmiddelet Roundup ufarlig?

Det mener Øystein Heggedal i et skriv i «Klassekampen» 7. september i år.<br/><br/>i 1980 var europeiske myndigheter kjent med at glyfosat kan gi fosterskader hos forsøksdyr. En dansk rapport fra 2012 viser at griser som

One man's year as 'Papa Goose'

WHEN the ornithologist Michael Quetting announced that he was going to play mother - or rather papa - goose to seven newly-hatched...<br/><br/>backs, which would transmit to ICARUS - International Cooperation for Animal Research Using Space. The ICARUS antennae were placed on the

Two-photon microscopy of Paneth cells in the small intestine of live mice

Paneth cells are one of the principal epithelial cell types in the small intestine, located at the base of intestinal crypts. Paneth cells...<br/><br/>when the weight reached 40~50 g. All animal experimental procedures were conducted in accordance with institutional guidelines and

Examining the Role of Cone-expressed RPE65 in Mouse Cone Function

Efficient chromophore supply is paramount for the continuous function of vertebrate cone photoreceptors. It is well established that...<br/><br/>were in accordance with the Guide for the Care and Use of Laboratory Animals and were approved by the Washington University Animal Studies

A Bioluminescent Cell Assay to Quantify Prion Protein Dimerization

The prion protein (PrP) is a cell surface protein that in disease misfolds and becomes infectious causing Creutzfeldt-Jakob disease in...<br/><br/>in accordance with legal regulations in Germany and all experimental protocols were approved by the DZNE’s Committee for Animal Experiments.

Misfolded SOD1 pathology in sporadic Amyotrophic Lateral Sclerosis

Aggregation of mutant superoxide dismutase 1 (SOD1) is a pathological hallmark of a subset of familial ALS patients. However, the possible...<br/><br/>Umeå University, Sweden. The Regional Ethical Committee for Animal Experiments approved experimental protocols involving animals beforehand,

Learning deficits in rats overexpressing the dopamine transporter

With its capacity to modulate motor control and motivational as well as cognitive functions dopamine is implicated in numerous...<br/><br/>or even adult stages. Materials and Methods Animals All animal experiments were carried out in accordance to the European Communities

Cortical Network Synchrony Under Applied Electrical Field in vitro

Introduction Synchronized neural activities underlie many cognitive and behavioral responses during normal brain functioning (Buzsaki and...<br/><br/>Use Committee and complies with the NIH Guide for the Care and Use of Laboratory Animals (IACUC # B2011-45). Cortices from embryonic day 18

Reducing Error in ECG Forward Simulations With Improved Source Sampling

A continuing challenge in validating electrocardiographic imaging (ECGI) is the persistent error in the associated forward problem observed...<br/><br/>University of Utah and conform to the Guide for the Care and Use of Laboratory Animals (National Institutes of Health publication No. 85-23)

Lægemidler skabes ved at finde 'molekylet i høstakken'

Der går en lang og kompliceret proces forud for ethvert nyt lægemiddel. Før man kan give medicin til mennesker, skal man nemlig finde de...<br/><br/>helt at undgå forsøgsdyr Sideløbende med afprøvning i raske forsøgsdyr afprøves lægemidlerne også i sygdomsmodeller, hvor syge forsøgsdyr

Alle taler om kollagen men hjælper det at spise proteinet?

Ansigtsolie med kollagen fra Elemis, 745 kr., ansigtsserum med kollagen fra Algenist, 765 kr., kollagenserum til ansigtet fra APOT.CARE,...<br/><br/>led, brusk, sener og ledbånd. "Og her ved vi overvejende fra dyreforsøg, at hydrolyserede kollagenpeptider, altså kollagen der er brudt i

How long until we bring woolly mammoths back from extinction?

Main image: Woolly mammoths were roughly the size of modern African Elephants, and weighed around six tonnes. Credit: Wikimedia CommonsPart...<br/><br/>Dr Mike McGrew, group leader at The Roslin Institute, an institute for animal research at the University of Edinburgh, to find out. Down to

European cancer research gets £30 million vote of confidence

UK and European research collaborations in cancer research have received a vote of confidence by three major cancer charities, with an...<br/><br/>trials. These methods will also help to reduce the level of animal research required. To read more Press Release articles, click here.

OVERBLIK: Milena Penkowas storhed og fald

Milena Penkowa havde stjerneforskerstatus. Siden blev hun dømt for underslæb og dokumentfalsk.<br/><br/>sigter hende for bedrageri og dokumentfalsk i forbindelse med en række påståede dyreforsøg i Spanien i 2003. Kammeradvokaten slår fast, at

CR UK forms £30m partnership with EU cancer charities

Cancer Research UK is partnering with European cancer research charities AIRC (Associazione Italiana per la Ricerca sul Cancro) and FC AECC...<br/><br/>risks for patients in clinical trials, and potentially also reduce the level of animal research required, the charity said. Also in the UK,

IFITM1 expression is crucial to gammaherpesvirus infection, in vivo

The oncogenic gammaherpesviruses, Epstein–Barr virus (EBV) and Kaposi’s sarcoma herpesvirus (KSHV), are etiologically associated with a...<br/><br/>was conducted to determine MHV-68 infection of lungs. All animal experiments were performed according to the European Union standards, and

CRUK forges £30m ‘post-Brexit’ R&D alliance

Joins forces with organisations in Italy and Spain<br/><br/>risks for those recruited into clinical trials and also reduce the need for animal research. In Italy, the University of Milan-Bicocca will

Vitamin D Toxicity–A Clinical Perspective

Confusion, apathy, recurrent vomiting, abdominal pain, polyuria, polydipsia, and dehydration are the most often noted clinical symptoms of...<br/><br/>VDT is based on anecdotal case reports, accidental poisoning, and animal experiments. For ethical reasons, experimentally analyzing VDT in

YAP drives cutaneous squamous cell carcinoma formation and progression

Squamous cell carcinoma (SCC) can progress to malignant metastatic cancer, including an aggressive subtype known as spindle cell carcinoma...<br/><br/>, or the decision to submit the work for publication. Ethics Animal experimentation: All animal-regulated procedures were carried out

Fitter Folks Suffer Milder Strokes: Study

HealthDay Reporter WEDNESDAY, Sept. 19, 2018 (HealthDay News) -- It's well-known that regular exercise can help cut your risk for a...<br/><br/>. Why would active seniors suffer less severe strokes? Spartano said that animal research offers some clues: Exercise seems to promote "

DiFusion’s ZFUZE Biomaterial Wins Best Spine Technology for 2018

– Orthopedics This Week annually recognizes the engineering teams and inventors who develop and successfully translate innovative products...<br/><br/>of this year’s Spine Technology Award due to the extensive animal research presented on ZFUZE Composite PEEK. The new biomaterial’s

DiFusion's ZFUZE™ Biomaterial Wins Best Spine Technology for 2018

AUSTIN, Texas, Sept. 19, 2018 /PRNewswire/ -- DiFusion Inc, a developer of advanced medical polymers utilizing novel zeolite technology,...<br/><br/>of this year's Spine Technology Award due to the extensive animal research presented on ZFUZE Composite PEEK. The new biomaterial's

Why BA refuses to carry lab animals

Airline facing legal battle over its blanket ban on transporting animals for medical research<br/><br/>willing to carry lab animals, because of “potential PR problems”. “Animal research is a global endeavour,” Leech continued. “They are bred

Herbal Bioenhancers in Veterinary Phytomedicine

Herbal bioenhancers are active phytomolecules that increase the bioavailability, bioefficacy and biological activity of various drugs when...<br/><br/>differences in these mechanisms, corresponding data on human and laboratory animal could not be attributed. As multidrug resistance is a

Man skulle tro, mobiltelefoni var harmløst

Læserbrev: I det seneste nummer af elektronikingeniørernes fagblad, IEEE Microwave Magazine, kan man læse en artikel om peer reviewet i...<br/><br/>binyrerne, og Lin opfordrer til at lave en komplet vævsanalyse af forsøgsdyrene for at afdække kræftrisikoen for kroppens øvrige væv. Og til

DiFusion’s ZFUZE™ Biomaterial Wins Best Spine Technology for 2018

Orthopedics This Week annually recognizes the engineering teams and inventors who develop and successfully translate innovative products...<br/><br/>of this year’s Spine Technology Award due to the extensive animal research presented on ZFUZE Composite PEEK. The new biomaterial’s

DiFusion's ZFUZE(TM) Biomaterial Wins Best Spine Technology for 2018

AUSTIN, Texas, Sept. 19, 2018 /PRNewswire/ -- DiFusion Inc, a developer of advanced medical polymers utilizing novel zeolite technology,...<br/><br/>of this year's Spine Technology Award due to the extensive animal research presented on ZFUZE Composite PEEK. The new biomaterial's

Insulin regulates POMC neuronal plasticity to control glucose metabolism

Hypothalamic neurons respond to nutritional cues by altering gene expression and neuronal excitability. The mechanisms that control such...<br/><br/>the decision to submit the work for publication. Ethics Animal experimentation: Experiments were approved by the Monash University School

Light-cured polymer electrodes for non-invasive EEG recordings

We invented the first non-metallic, self-adhesive and dry biosignalling electrode. The PEDOT polymer electrode changes its aggregate state...<br/><br/>precise handling of the PEDOT polymer electrode. Materials and Methods Animal Experiments We took EEG recordings of 6 newborn piglets.

Optogenetic Peripheral Nerve Immunogenicity

Optogenetic technologies have been the subject of great excitement within the scientific community for their ability to demystify complex...<br/><br/>prior to their clinical and commercial implementations. Methods All animal experiments were conducted on Fischer 344 or Sprague Dawley

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