Guide to the Necropsy of the Mouse

By Vincenzo Covelli

This handbook aims is to be an essential guide on autopsy techniques for people who work with experimental animals and in particular with the mouse.

Type: Web pages. Category: Anatomy (animal), Dissection (animal) & Pathology (animal).

Table of Contents:
Index; Preface
1 Introduction: General; Materials; Description of autopsy cards; Collection and fixation criteria for histological examination
2 External Examination: General condition; Skin and cutaneous adnexae; Natural orifices
3 Internal Examination: Subcutaneous; Superficial and deep lymph nodes; Mammary glands; Skeleton and skeletal musculature
4 Abdominal cavity: Opening and general examination; Spleen; Pancreas; Digestive system; Liver and biliary ducts; Urinary apparatus; Female genital apparatus; Male genital apparatus
5 Thoracic Cavity: Opening and general examination; Thymus; Lungs and heart; Thyroid
6 Cranial Cavity: Opening and general examination; Eye; Harderian gland; Brain.
Preparation of tissues for histopathology
Bibliography.

Comes with explanatory text and figures (colour photographs, drawings and tables).

This resource is no longer available online, but the Guide is available free of charge from the STOREDB database.

The necropsy guide was written by Vincenzo Covelli, ENEA, CR-Casaccia, Rome, Italy and based on his original guide published by Boringhieri in 1972. This edition includes new images taken for this purpose with the assistance of Vincenzo Di Maio. The project was funded as part of the EULEP - Web Atlas of Pathology (www.eulep.org), a
project funded by the European Commission (Contract number QLRT-1999-00320).

Please also see the necropsy section of the PREPARE guidelines for more resources.

This page was updated on 06 October 2025
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