Strathclyde Pharmacology Simulations: RatCVS

By John Dempster

RatCVS belongs to The Strathclyde Pharmacology Simulations package that simulates pharmacological experiments on isolated tissues or whole animals. Type of record: Computer Program and Web Pages. Category: Pharmacology

Ratcvs

RatCVS (Cardiovascular System) belongs to The Strathclyde Pharmacology Simulations package that simulates pharmacological experiments on isolated tissues or whole animals. A range of drugs in varying concentrations can be applied and the effects observed. RatCVS is a simulation of the pithed rat experimental preparation for investigating the actions of drugs on the heart and cardiovascular system. "Pithing" refers to the destruction of spinal cord pathways, severing all the nerve connections between the brain and the cardiovascular system, simplifying the interpretation of experimental results by removing the central baroreceptor reflexes.
This simulation allows you to observe traces of blood pressure, left ventricular pressure, venous pressure, heart rate and contractile force on a simulated chart recorder, to apply a variety of different drugs, and to observe their effects.

Installation information is available at the bottom of this page: http://spider.science.strath.ac.uk/sipbs/page.php?page=software_sims

Please see The Virtual Cat, The Virtual Organ Bath, The Virtual Nerve, The Virtual Twitch, EPSim (Rat Brain Slice Epilepsy Simulation) and The Virtual NMJ (Neuromuscular Junction) for the other simulations in this package.

Please read the Conditions under which the software may be used.

Version: Version 3.3.6, 2020

Computer program: Windows 95 or later

Price:
Academic users, others working for non-commercial, non-profit making organisations: Free of charge.
Commercial organisations: Purchase a licence to use the software from the University of Strathclyde (contact the author for details).

See also the physiology and pharmacology programs produced by David Dewhurst for similar resources.

Links to more pharmacology simulations

Links to alternatives to rat dissections

Links to all types of dissection alternative

This page was updated on 26 April 2022

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