Sourcebook of Models for Biomedical Research

By editor Conn, P. Michael

Sourcebook of Models for Biomed Research

This book offers a reflection of the diversity and utility of models used in biomedicine. That utility is based on the consideration that observations made in particular organisms will provide insight into the workings of other, more complex systems. Some models have the advantage that the reproductive, mitotic, development or aging cycles are rapid compared with those in humans; others are utilised because individual proteins may be studied in an advantageous way and have human homologs. Other organisms are facile to grow in laboratory settings, lend themselves to convenient analyses, have defined genomes or present especially good human models of human or animal disease. This book is a comprehensive and extensive collection of these important medical parallels.
The book contains the following chapters:

  • Animal Models for Human Diseases
  • Selection of Biomedical Animal Models
  • Improved Models for Animal Research
  • The Ethical Basis for Animal Use in Research
  • Bibliographic Searching Tools on Disease
  • Models to Locate Alternatives for Animals in Research
  • NIH Policies on Sharing of Model Organisms and Related Research Resources
  • Databases for Biomedical Animal Resources
  • Psychological Enrichment for Animals in Captivity
  • Integrated Network Modeling of Molecular and Genetic Interactions
  • The Sponge as a Model of Cellular Recognition
  • Sea Urchin Embryo
  • Caenorhabditis elegans
  • Models of Human Neurodegenerative Diseases
  • Zebrafish as a Model for Development
  • Zebrafish as a Model for Studying Adult Effects of Challenges to the Embryonic Nervous System
  • Modeling Cognitive and Neurodegenerative Disorders in Drosophila melanogaster
  • Biomedical Research with Honey Bees
  • Establishing and Maintaining a Xenopus laevis Colony for Research Laboratories
  • The Chicken as a Model Organism
  • Rat Knockout and Mutant Models
  • Rodent Genetics, Models, and Genotyping Methods
  • The House Mouse in Biomedical Research
  • Mouse Model for Alzheimer’s Disease
  • Guinea Pigs as Models for Human Cholesterol and Lipoprotein Metabolism
  • Reliability of Rodent Models
  • The Domestic Cat, Felis catus, as a Model of Hereditary and Infectious Disease
  • Swine in Biomedical Research
  • The Minipig as an Animal Model in Biomedical Stem Cell Research
  • The Nonhuman Primate as a Model for Biomedical Research
  • Primates as Models of Behavior in Biomedical Research
  • Primate Models for Understanding Brain Mechanisms of Cognitive Behavior
  • Animal Models for Eye Diseases and Therapeutics
  • Animal Models of Noise-Induced Hearing Loss
  • Human and Animal Models for the Study of Muscle Pain
  • Animal Models of Parkinson’s Disease
  • Transgenic Animal Models of Neurodegenerative Diseases
  • Animal Models of Nociception and Pain
  • Nonmammalian Models for the Study of Pain
  • Animal Models of Vascular Development and Endothelial Cell Biology
  • Models of Behavior Animal Models for Atherosclerosis, Restenosis, and Endovascular Aneurysm Repair
  • Transgenic mouse models of HIV-1/AIDS and cardiac performance
  • Primate Models for the Assisted Reproductive Technologies and Embryonic Stem Cell Biology
  • Rat Models of Polycystic Ovary Syndrome
  • Murine Models for Reproduction

Comments & References: 537 pages. Available as a Hardcover and as an eBook. Suitable for pharmaceutical and academic researchers across a wide range of biological fields. Each chapter may be purchased separately.

ISBN: Hardcover: 978-1-58829-933-8; eBook: 978-1-59745-285-4

Price: Hardcover: US$409.00; eBook: US$319.00; Individual chapter: US$29.95


Year: 2008
This page was updated on 20 March 2020

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