The Mouse in Biomedical Research: History, Wild Mice and Genetics, Volume 1, Second Edition
By Fox, James G.; Barthold, Stephen; Davisson, Muriel; Newcomer, Christian; Quimby, Fred & Smith, Abigail
| Record number: | c638c (legacy id: 6057) |
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This title provides information about the history, biology and genomics of the laboratory mouse (Mus musculus), as well as basic information on maintenance and use of mouse stocks. Mouse origins and relationships are covered in chapters on history, evolutionary taxonomy and wild mice. Genetics and genomics of the mouse are discussed in chapters on genetic nomenclature, gene mapping, cytogenetics and the molecular organization of the mouse genome. Use of the mouse as a model system for basic biomedical research is described in chapters on chemical mutagenesis, gene trapping, pharmacogenetics and embryo manipulation.
Table of Contents: 1 Building a Better Mouse: One Hundred Years of Genetics and Biology; 2 Systematics of the genus Mus; 3 The Secret World of Wild Mice; 4 Breeding Systems: Considerations, Genetic Fundamentals, Genetic Background, and Strain Types; 5 Mouse Strain and Genetic Nomenclature: an Abbreviated Guide; 6 The Mouse Genome; 7 Gene Mapping; 8 Genetic Monitoring; 9 Cytogenetics; 10 Mouse Embryology: Research Techniques and a Comparison of Embryonic Development between Mouse and Man; 11 Gamete and Embryo Manipulation; 12 Chemical Mutagenesis in Mice; 13 Gene-Specific Mutagenesis; 14 Gene Transfer Studies Using Mouse Models; 15 Mouse and Human Pluripotent Stem Cells; 16 Drugs and the Mouse: Pharmacology, Pharmacogenetics, and Pharmacogenomics.
Second Edition. Includes 16 chapters. 352 pages. Available as a Hardcover + eBook, Hardcover only and as an eBook only. This title is the first (Volume 1) in a series of 4 volumes with comprehensive coverage of all aspects of mouse biology and breeding. Please see record numbers 6053, 6054 and 6082 for Volumes 2, 3 and 4 in this series. All four books in this series are also available as One Volume (2192 pages, ISBN: 0-12-369454-X, 2006). This textbook is sponsored by the American College of Laboratory Animal Medicine (ACLAM). Published by Academic Press, now part of Elsevier.
ISBN: Hardcover: 9780123694553; eBook:9780080469065
Price: Hardcover + eBook: €107.50; Hardcover only: €82.50; eBook only: €78.75
Year: 2006
This is one of our favourite textbooks within Laboratory Animal Science.
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