DrugMatrix

DrugMatrix, produced by the U.S. National Toxicology Program, is a molecular toxicology reference database and informatics system.

DrugMatrix, produced by the U.S. National Toxicology Program, is a molecular toxicology reference database and informatics system. DrugMatrix is populated with the comprehensive results of thousands of highly controlled and standardized toxicological experiments in which rats or primary rat hepatocytes were systematically treated with therapeutic, industrial, and environmental chemicals at both non-toxic and toxic doses.

Following administration of these compounds in vivo, comprehensive studies of the effects of these compounds were carried out at multiple time points and in multiple target organs.

The heart of the DrugMatrix database is large-scale gene expression data. The primary value that DrugMatrix provides to the toxicology community is in its capacity to use toxicogenomic data to perform rapid toxicological evaluations.

The resource is no longer hosted for external use, but the data is available in a number of formats.

This page was updated on 13 March 2019

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