ToxCast
| Record number: | 43e7d (legacy id: 15312) |
|---|---|
| Category: | Toxicology |
| Type: | Information centres - Databases |
| Relevance: | Reduction - Replacement |
A major part of the U.S. Environmental Protection Agency's computational toxicology research is the Toxicity Forecaster (ToxCast). ToxCast is a multiyear effort launched in 2007 that uses automated chemical screening technologies, called ?highthroughput screening assays?, to expose living cells or isolated proteins to chemicals. The cells or proteins then are screened for changes in biological activity that may suggest potential toxic effects. These innovative methods have the potential to limit the number of required animal-based laboratory toxicity tests while, quickly and efficiently screening large numbers of chemicals.
As part of EPA's commitment to gather and share its chemical data in open and transparent ways, all ToxCast chemical data is publicly available for anyone to access and use through user-friendly web applications called interactive Chemical Safety for Sustainability Dashboards (iCSS).
More information and access to ToxCast data is here.
A fact sheet about Toxcast can be downloaded here.
See also Norecopa's collection of links to alternatives databases
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