TSAR: Tracking System for Alternative test methods Review, Validation and Approval in the Context of EU Regulations on Chemicals

By IHCP Communication Office European Commission, Joint Research Centre Institute for Health and Consumer Protection Via E. Fermi 2749 21027 Ispra (Varese) Italy phone: +39 0332 78 9111 E-mail: jrc-ihcp-communication@ec.europa.eu Website: http://ihcp.jrc.ec.europa.eu

A tool to provide information on the status of alternative methods as they progress from scientific protocols to validation for being used in a regulatory context.

The Joint Research Centre's EU Reference Laboratory for Alternative to Animal Testing (EURL ECVAM) has produced a Tracking System for Alternative methods towards Regulatory acceptance (TSAR). 

TSAR provides information on the status of alternative methods as they progress from scientific protocols to validation for being used in a regulatory context. The process of validation and regulatory approval has been broken down into a number of steps. Although this is a continuous process that may, sometimes, also involve some iterations, for practical reasons it has been broken down into two parts:

  • Review and Validation
  • Regulatory Approval

These have, in turn, been broken down into several stages. The methods whose status of validation or regulatory acceptance are tracked here have been grouped by the relevant endpoint they cover.

A revised version of TSAR, launched in 2016, provides enhanced visibility of the progress a test method makes from first being proposed for validation through to its eventual acceptance for regulatory safety and efficacy testing of chemicals or biological agents. TSAR includes summary descriptions of individual methods and all available records associated with different steps of the validation and acceptance process.

TSAR disseminates information on test methods not only under consideration by EURL ECVAM but by all member and observer organisations of the International Collaboration on Alternative Testing Methods (ICATM) representing the EU, Canada, USA, Republic of Korea, Japan, Brazil and China.

The database is free.

This page was updated on 21 December 2023

Did you find what you were looking for?

Yes, I found it! No, I did not!

Thanks for your feedback! Please note that we cannot reply to you unless you send us an email.

What are you looking for?

We value your feedback so we can improve the information on the page. Please add your email address if you would like a reply. Thank you in advance for your help.!

Please contact us by email if you have any questions.

Thanks for your feedback! Please note that we cannot reply to you unless you send us an email.

RadioButtonList field
 

Abonnér på nyhetsbrevene fra Norecopa