FRAME Training School in Experimental Design and Statistical Analysis of Biomedical Experiments.
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Owner/Developer: Fund for the Replacement of Animals in Medical Experiments (FRAME)
02 January 2008
Previous funders include: COST Action B24; Laboratory Animals Limited; European Partnership for Alternative Approaches to Animal Testing (EPAA); Norwegian Society for Protection of Animals (Dyrebeskyttelsen Norge); Network of Animal Disease Infectiology Research Facilities (NADIR). The next event will be supported by Veterinary Biocontained facility Network (VetBioNet).
Nottingham. However, the event takes place in different countries and cities to meet demand. Previous locations have been, Manchester (UK), Edinburgh (UK), Porto (Portugal), Coimbra (Portugal), Voss (Norway), Nijmegen (Netherlands), Copenhagen (Denmark) and Saskatoon (Canada).
FRAME delivers regular training schools in experimental design and statistics to increase awareness among scientists about the need to reduce animal numbers in experiments and to refine procedures. Participants gain a better understanding of how to properly design and effectively analyse their experimental programmes so that they can go on to produce higher quality science, which has made the most efficient use of a minimum number of animals. This Training School is an ideal opportunity to facilitate dialogue and enhance the application of experimental design and statistical analysis to animal experimentation to improve: a) animal welfare; b) the amount of information from a given number of animals involved and c) the quality of biomedical research and testing.
The key objectives of the Training School are: to provide researchers with an understanding of basic design concepts that they do not seem to be gaining from other sources; to give researchers the ability to use more efficient designs for their experiments; and to stimulate engagement with the 3Rs and useful discussion between animal users in industry and academia on both refinement and reduction.
Computer assisted learning, Lecture, Workshops
Optional / Voluntary
Postgraduate level of education with some basic experience of statistics and experimental design, Participants must be working with or about to begin working with laboratory animals, or work in a capacity where they will be advising those who work with laboratory animals (e.g. regulatory inspectors or facility managers).
Students, Researchers, Regulators and policy-makers, Teachers and educators, Technicians, Managers, Scientific officers / Project managers, Professionals (e.g. veterinarians)
Academia, Industry, Governmental bodies, Contract Research Organizations (CROs), SMEs
University (Doctoral education), Postdoctoral (teaching and research), Continuing Professional Development
Designing procedures and projects
Full coverage (a dedicated course)
No species is addressed specifically
|Details on the topic or technology covered:||
The programme is structured to lead the participants from simple experimental design and statistical ideas, through more complex methods and analysis to effective presentation of findings. Participants are able to discuss their own research problems/experiences with the Training School tutors. The main themes are: Basic Principles; Experimental Designs and Statistical Analysis; and Applied Experimental Design and Presentation for Publication.
Directive 2010/63/EU or equivalent
The group work aims to enable application of the information provided in the lectures. The tasks enable group problem solving and reinforce understanding of the material being covered. The specific learning outcomes that are incorporated into the group work are:
1. Identifying suitable research objectives, controls and experimental units (EU Outcome 10.3/10.4)
2. Identifying common basic faults in experimental design and data presentation (EU Outcome 10.3/10.4)
3. Identifying the correct experimental design for a given objective (EU Outcome 10.7)
4. Being aware of the Arrive Guidelines and designing an experimental protocol that would meet them (EU Outcome 10.7/11.9)
|Accreditation body and/or authority that approved the education or training:||
FELASA – Federation for Laboratory Animal Science Associations
LASA – Laboratory Animal Science Association.
10 LASA (UK) CPD points.
|Statistic of impact:||
A survey was conducted after the first two events and the results were published: Howard, B, Hudson, M and Preziosi R (2009) More is Less: Reducing Animal Use by Raising Awareness of the Principles of Efficient Study Design and Analysis. ATLA, 37: 33-42.
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