Health Sciences Master
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Owner/Developer: University of Minho, School of Health Sciences
|Description:||Laboratory Animal Sciences module, part of the Health Sciences Master. This Master program offers to holders of BSc, essentially in the area of biological and biomedical sciences, expertise in the area of health sciences. During the curricular year, students will approach the basis of several major biomedical scientific areas, acquire laboratory and research skills and competences, and elaborate the thesis project proposal. In the second year students will develop competencies of autonomy in conducting experimental work and of interpreting data. This course takes place at the School of Health Sciences and its Institute of Life Sciences and Health (ICVS).|
Hands-on training, Lecture
Candidates to the Master in Health Sciences must be holders of a degree, or legal equivalent in a field of biological and biomedical sciences
Refinement, Reduction, Replacement
Carrying out procedures on animals, Designing procedures and projects, Taking care of animals, Killing animals, Ethics
Partial coverage (e.g. a module)
No species is addressed specifically
|Course level on animal species:||
|Details on the topic or technology covered:||
- Introduction to Laboratory Animal Science;
-Ethics in animal-based research and the concept of the 3Rs;
-Behavior/stress/well-being for different species, gender and age categories;
-Welfare during experimental procedures;
-Alternatives to animal procedures;
-Diseases of laboratory animals, microbiology and gnotobiology and methods to maintain the correct sanitary status;
-Nutrition of laboratory animals (requisites for distinct species, age category and physiologic conditions);
-Principals of genetic standardization, genetic manipulations (transgenic and KO strains) and embryo cryopreservation;
-(Micro)surgical techniques/telemetry; peri-operative care, anesthesia, analgesia and euthanasia; -
-Statistical analysis for experimental planning and data analysis;
-Portuguese and International Legislation for the use of the use of laboratory animals;
-Handling of laboratory animals, techniques to administer substances and to collect biological samples.
1. Name the requirements of the most commonly used laboratory animal species with respect to housing, nutrition and care.
2. Recognize signs of pain as well as discomfort in laboratory animals and to define humane endpoints.
3. Name the more important characteristics of the animal house and cages in accordance with animal welfare.
4. Be aware of the possible impact of environmental and procedural factors on animal welfare and experimental results.
5. Be familiar with the basics of animal handling and also obtained some practical experience in this respect.
6. Gain practical experience in the oral administration of substances and the performance of various injection techniques.
7. Understand the advantages and disadvantages of the different methods for the collection of body fluids and administration of substances (amongst others like gavage, injections, cannulation, insertion of catheters, etc.).
8. Enumerate the most important methods of euthanasia, and discriminate the ones that should be used for the different laboratory animal species in distinct situations (applicability to different experimental settings, advantages and disadvantages).
9. Be familiar with the different methods of anesthesia and analgesia that should be correctly applied in different settings (animal species, type of procedure, animal age, etc.).
10. Be acquainted with the importance of hygienic measures and barrier systems to maintain the sanitary status of the animals in the animal house.
11. Recognize the impact of animal diseases on the experimental approach and the importance of health monitoring protocols.
12. Identify relevant rules in respect to safety and occupational health when working with laboratory animals.
13. Identify the specific demands that are necessary for a correct preparation and performance of animal experimental techniques and research.
14. Correctly apply basic notions of statistics to optimize the use of laboratory animals and the analysis of results.
15. Identify potential alternative techniques to the use of laboratory animals.
16. Be familiar with legislation concerning the use of laboratory animals.
17. Identify and discuss basic principles, which guide towards the ethical judgment of animal experiments.
|Accreditation body and/or authority that approved the education or training:||
The contents have been defined to meet the requirements of the "Federation of European Laboratory Animal Science Associations (FELASA)" for obtaining Category C FELASA certification
Master of Science (60 ECTS / year).
LAS course: 10 ECTS
Category C FELASA certification
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