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Owner/Developer: Technische Universität München (TUM)
01 April 2018
The dynamic activity of the cellular core metabolism is a key functional parameter for the assessment of living cells. The course gives an introduction into cell physiological aspects and continues with the engineering and analytical approaches that are used to record cell metabolism on a microscale. In this context, the complete system engineering background needed to comprehend the function of microphysiometric devices (including microsensing, microfluidics, electronics, cell culture maintenance systems, firmware, software for data evaluation) is outlined.
The exercises are given problems to be solved, demonstrations and experimental group work. Moreover, the students have the opportunity to contribute with an own presentation about a selected topic of microphysiometry, prepared in homework.
Computational methods, In vitro methods, Ethics, Legislative aspects
Directive 2010/63/EU or equivalent, REACH Regulation (EC) No 1907/2006 or equivalent, Cosmetics Regulation (EC) No 1223/2009 or equivalent, Medical Devices Regulation (EU) 2017/745, In Vitro Diagnostic Medical Devices Regulation (EU) 2017/746, Food Safety (EC) No 178/2002 or equivalent, Test guidelines (OECD, ISO, etc.)
After completion of the module the students are able to
• understand the basic principles of cellular energy metabolism;
• to understand and to apply important system engineering methods needed for microphysiometry;
• to analyse and to evaluate the specific requirements of live cell assays in settings of diagnostics, pharmaceutical or toxicological research.
|Accreditation body and/or authority that approved the education or training:||
Technische Universität München
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