Toxicology 21: Scientific Applications (1) (Toxicology 21: Scientific Applications)
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Owner/Developer: Johns Hopkins University (JHU)
| Country: |
United States of America |
|---|---|
| Languages: |
English |
| Url: |
https://www.jhsph.edu/courses/course/25182/2017/187.645.81/toxicology-21-scientific-applications |
| Locations: |
United States of America |
| Description: | Familiarizes students with the novel concepts being used to revamp regulatory toxicology in response to a breakthrough National Research Council Report “Toxicity Testing in the 21st Century: A Vision and a Strategy.” Presents the latest developments in the toxicology field: moving away from animal testing toward human relevant, high content, high throughput integrative testing strategies. Active programs from EPA, NIH and the scientific community work-wide illustrate the dynamics of safety sciences. |
| Format: |
Interactive online resources, Lecture |
| Presence: |
Mandatory, Optional / Voluntary |
| Access: |
In-house training |
| Content type: |
Theoretical, Practical |
| Duration: |
24 hours |
| Prerequisites: |
For Johns Hopkins enrolled students: master of health sciences, master of science in public health, master of science, PhD programs. Background in molecular and cell biology. |
| Target audience: |
Students, Researchers |
| Target sectors: |
Academia |
| Educational level: |
University (Master), University (Doctoral education) |
| 3rs relevance: |
Replacement, Reduction |
| Topics covered: |
Computational methods, In vitro methods |
| Details on the topic or technology covered: |
Session topics will cover the concept of Toxicology of 21st century, its goals and rationale: In vitro toxicology High throughput screening strategies High content test strategies 3D organotypic human relevant models for toxicity testing:organ-on-chip; human-on-chip approaches Pathway of Toxicity (PoT) Adverse Outcome Pathways (AOP) Bioinformatics for information-rich data analysis NTP/NIH Tox21 program: results and implementation EPA ToxCast program, results and implementation |
| Legislative framework: |
REACH Regulation (EC) No 1907/2006 or equivalent, Test guidelines (OECD, ISO, etc.) |
| Accreditation body and/or authority that approved the education or training: |
JHU |
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