By "alternatives" to the use of animals in research, Norecopa endorses the internationally accepted tenet of The Three R's (Replacement, Reduction, Refinement), developed by Russell and Burch in the UK in the 1950s. The Three S's of Carol Newton are a good adjunct to the three R's.
The PREPARE guidelines and their associated webpages give comprehensive guidance on how to plan animal experiments in the spirit of these principles.
Alternatives to dissections
Alternatives validated by the OECD
Alternatives validated by EURL ECVAM
The European Pharmacopeia
Alternatives to animal testing: a review
Alternatives to animal testing
Alternatives and Searching the Literature for Animal Research (UC Davis website)
Alternative research (3Rs) in the World, Asia and Japan
What you need to know about organoids
Alternative laboratory animals (outside present-day legislation):
The roundworm C. elegans (Caenorhabditis elegans)
The fruit fly (Drosophila melanogaster)
Non-traditional laboratory animals (covered by present-day legislation):
The naked mole rat (Heterocephalus glaber)
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