3D printing of PLGA scaffolds for tissue engineering (1)
Owner/Developer: Biomedical Materials Research
|Country:||United States of America|
We proposed a novel method of generation of bioresorbable polymeric scaffolds with specified architectonics for tissue engineering using extrusion three-dimensional (3D) printing with solutions of polylactoglycolide in tetraglycol with their subsequent solidifying in aqueous medium. On the basis of 3D computer models, we obtained the matrix structures with interconnected system of pores ranging in size from 0.5 to 500 µm. The results of in vitro studies using cultures of line NIH 3Т3 mouse fibroblasts, floating islet cultures of newborn rabbit pancreas, and mesenchymal stem cells of human adipose tissue demonstrated the absence of cytotoxicity and good adhesive properties of scaffolds in regard to the cell cultures chosen.
|Audience:||Scientists - Students - Industry - Researchers|
|User access:||Fee-based access|
|Purpose:||Method development - Documentation and information|
|Technology/Tools:||3D printing - Tissue engineering|
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