GUIDANCE ON A STRATEGY FOR GENOTOXICITY TESTING
Owner/Developer: The Committee on Mutagenicity of Chemicals in Food, Consumer Products and the Environment (COM)
The Committee on Mutagenicity of Chemicals in Food, Consumer Products and the Environment (COM) has a remit to provide UK Government Departments and Agencies with advice on the most suitable approaches to testing chemical substances for genotoxicity. The COM published guidance in 1981, 1989 and again in 2000. This document, incorporating some significant changes, reports on the COM views regarding the most appropriate strategy for genotoxicity testing reached in 2011.
|User access:||Open access|
|Relevance:||Replacement - Reduction - Refinement|
|Purpose:||Toxicological and safety evaluation - Documentation and information|
|Technology/Tools:||Alternative test methods (in vitro) - Animal testing (in vivo)|
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