Profiling the toxicity of new drugs: a non animal-based approach integrating toxicodynamics and biokinetics (Predict-IV)
Owner/Developer: European Commission (EC)
The overall aim of Predict-IV was to develop strategies to improve the assessment of drug safety in the early stage of development and late discovery phase, by an intelligent combination of non animal-based test systems, cell biology, mechanistic toxicology and in-silico modelling, in a rapid and cost effective manner.
|Audience:||Scientists - Industry - Researchers|
|User access:||Open access|
|Relevance:||Replacement - Reduction - Refinement|
|Purpose:||Toxicological and safety evaluation - Regulatory testing - Method development|
|Legislative framework:||Medicines legislation|
|Technology/Tools:||Alternative test methods (in vitro) - Non-testing methods (in silico) - Omics|
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