Virtual Physiology: SimHeart
| Record number: | cb8a9 (legacy id: 9194) |
|---|---|
| Category: | Pharmacology - Physiology |
| Type: | Computer Program |
SimHeart offers a virtual laboratory for recordings of heart contractions in the Langendorff set-up
in response on the most relevant transmitters and drugs, including a drug laboratory for the adjustment of the appropriate solutions.
Featured experiments:
Effects of Adrenaline and Acetylcholine on frequency and amplitude of heart contractions
(inotroph and chronotroph effects), effects of competitive receptor blockers Propranolol and Atropine,
adrenaline dose-response curve and its shift by the ß-blocker Propranolol (competitive inhibition),
comparison with non-competitive inhibition by the Ca2+-channel blocker Verapamil,
strengthening of the contractions by the heart-glycoside g-Strophantine, induction and treatment of arrhythmias and heart blocks in systole and diastole.
First version published October 07, 2013. Last update December 19, 2015.
- Download a fully functioning DEMO Version.
- Please watch Video; SimHeart - Preparation of an isolated Heart of the Rat.
SimHeart is a part of Virtual Physiology Series that consists of 5 interactive simulation CD-ROMS:
The series covers the entire field of nerve-muscle physiology and simulates all of the classic experiments conducted by medical, dental, veterinary, biology and chemistry students. All stimulation and recording devices are freely adjustable. Mathematical algorithms guarantee for the appropriate reactions of the preparations in all situations, also considering their physiological diversity.
Programs running on all Windows platforms, from Win XP to Win 10, 32 bit as well as 64 bit
versions. SimHeart and SimVessel also include .swf files to run on MacOS.
It is part of the cLABs set produced by Professor Hans Braun (see also record numbers 5406 and 5407).
Price: Please see Virtual-Physiology.
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