Monoclonal Antibody Production

Table of Contents: Front Matter; Executive Summary; Introduction; Generation of Hybridomas: Permanent Cell Lines Secreting Monoclonal Antibodies; In Vitro Production of Monoclonal Antibody; Scientific Needs for Mouse Ascites Production of mAb; Summary of Advantages and Disadvantages of In Vitro and In Vivo Methods; Large-Scale Production of Monoclonal Antibodies; Animal-Welfare Issues Related to the Ascites Method for Producing Monoclonal Antibodies; Conclusions and Recommendations; References; Appendix A: Workshop on Methods of Producing Monoclonal Antibodies; Appendix B: Biographical Sketches of Authoring Committee.

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