Using computational models to predict fish acute toxicity of pesticide metabolites
Owner/Developer: National Centre for the Replacement, Refinement & Reduction of Animals in Research (NC3Rs)
An analysis, published recently in Regulatory Toxicology and Pharmacology, has shown that Quantitative Structure–Activity Relationship (QSAR) models could potentially be used to predict whether plant protection product (PPP) metabolites are acutely toxic to fish. The work was led by the NC3Rs, in partnership with scientists from Dow AgroSciences, Syngenta and BASF.
|Audience:||Scientists - Regulators - Industry|
|User access:||Open access|
|Updating frequency:||13 July 2016|
|Relevance:||Replacement - Reduction|
|Purpose:||Toxicological and safety evaluation - Documentation and information|
|Technology/Tools:||Non-testing methods (in silico)|
Did you find what you were looking for?Yes, I found it! No, I did not!
Thanks for your feedback! Please note that we cannot respond unless you supply your email address.
What are you looking for?
Please give us your feedback so we can improve the information on the page. Thank you in advance for your help. Please add your email address if you would like a reply.Please contact us by email if you have any questions.