Nonhuman Primate Models in Biomedical Research: State of the Science and Future Needs

By National Academies of Sciences, Engineering, and Medicine; Health and Medicine Division; Division on Earth and Life Studies; Board on Health Sciences Policy; Institute for Laboratory Animal Research; Committee on the State of the Science and Future Needs for Nonhuman Primate Model Systems; Kenneth S. Ramos, Autumn Downey, and Olivia C. Yost, Editors

Nonhuman Primate Models In Biomedical Research State Of The Science And Future Needs

Nonhuman Primate Models in Biomedical Research: State of the Science and Future Needs is a consensus study report published by National Academies of Sciences, Engineering, and Medicine. At the direction of the U.S. Congress, NIH asked the National Academies of Sciences, Engineering, and Medicine to convene an expert committee to conduct a landscape analysis of current and future use of nonhuman primates in NIH-supported biomedical research, as well as opportunities for new approach methodologies to complement or reduce reliance on nonhuman primate models. This consensus study report provides the committee findings and conclusions.

Nonhuman primates represent a small fraction of animals used in biomedical research, but they remain important research models due to their similarities to humans with respect to genetic makeup, anatomy, physiology, and behavior. Limitations in the availability of nonhuman primates have been exacerbated by the COVID-19 pandemic and recent restrictions on their exportation and transportation, impacting National Institutes of Health (NIH)-funded research necessary for both public health and national security. Additionally, there is continued interest in understanding whether and how nonanimal models can be used to answer scientific questions for which nonhuman primates are currently used.

268 pages. Table of Contents

ISBN: Prepublication:  978-0-309-69933-4
ISBN Paperback (forthcoming):  978-0-309-69936-5

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Year: 2023
This page was updated on 10 May 2023

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