Many more links to specific guidance on literature searching, databases and systematic reviews are available in a separate section of this website.
Systematic reviews can be used not only to determine the need for more studies, but also for "synthesis of evidence": drawing new conclusions from already published data: 'Towards Evidence-Based Research'.
Using The Replacement Checklist and a worked example of a literature search
Replacing Animal Research have produced a worked example of a literature search, looking for alternatives to animals in studies of Multiple Sclerosis. They have also produced The Replacement Checklist to assist researchers in identifying Replacement Alternatives to animal use. See also:
- Dukes, Beale & Camp (2025): Reviewing Current Guidance for the 'R' of Replacement and Rethinking it with the 'Replacement Checklist'
- A recorded webinar about use of the checklist
More resources